Whole Body Image Acquisition in Less Than One Minute

X-O™, Gamma Medica-Ideas’ micro-CT system, has the flexibility to perform a range of image acquisitions, from fast whole body image acquisitions that take less than a minute, to very-high-resolution whole body scans. In fact, our X-O system has the highest resolution for CT imaging. It has the largest field of view in the industry, allowing researchers to image large subjects. X-O combines the most advanced GOS/CMOS based digital x-ray detector technology with real-time image reconstruction and the latest 3-D rendering applications software.

Micro-CT is useful for a broad range of biological and physiological studies in vivo in pre-clinical models. Specifically, in vivo studies with micro-CT allow investigators to monitor disease processes and progression, detect genetically based morphological changes, and evaluate the effects of treatment. Micro-CT allows this to be done faster and with fewer subjects than in the past.

Unparalleled Imaging Flexibility

X-O features set imaging parameters ranging from fast image acquisition in under a minute to very high-resolution scans. Variable acquisition times allow researchers to use a wide variety of contrast agents and to design imaging protocols specifically suited to their particular studies. For example, widely-used Iodine-based intravenous contrast agents wash out of mice in under a minute. Researchers can use these agents with X-O, because sub-minute scans can be accomplished.

Largest field of view

GM-I’s X-O system allows researchers to image the largest range of test subjects of any micro CT system, with a 9.3 cm diameter by 9.7 cm axial field of view.

Lowest dose

Protect the integrity of your study by ensuring your results are not affected by the x-ray dose. X-O’s dose is less than 2cGy in a sixty-second scan.

Fully shielded

X-O can be operated in any laboratory environment. It requires no special shielding. Meets 21 CFR 1020.40 requirements.

Upgradeable to Multi-Modality System

X-O uses the same FLEX Triumph^TM Platform as GM-I’s X-SPECT^®, X-PET^TM and LabPET^TM systems. It can easily be upgraded, on site, to a SPECT/CT or PET/CT system.

Viewing software

Visualization software with transaxial, sagittal and coronal views, views form arbitrary angles, contrast adjustment, surface and volumetric rendering, region of interest (ROI) definition capability, and automatic segmentation.

Applications

Micro-CT is used for:

• Rapid screening of anatomical abnormalities, including phenotype differentiation of mutagenic species
• Vascular imaging, including study of angiogenesis, especially when used with contrast enhancement media soft tissue and tumor imaging to differentiate normal tissue from tumors
• Identification of lung nodules
• Monitoring cancer progression and regression to study the impact of cancer therapies, including immunotherapy, chemotherapy, and radiation therapy
• Skeletal studies, in particular arthritis research and bone mineral density evaluation to study osteoporosis
• Volumetric measurement of organs and tissues

For more information please visit
www.gehealthcare.com/preclinical
or send inquiry to
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